Results 181 to 190 of about 3,398,903 (291)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Computed Tomographic Volumetric Analysis of the Nasal Cavities in Domestic Cats (Felis catus) and Anatomical Implications for Intranasal Drug Delivery. [PDF]

Anat Histol Embryol
Charles M, Hippolyte C, Charlène P, Géraldine J, Giovanni M.   +4 more
europepmc   +1 more source

UIU VC Appointed News 2018 - Observer

, 2018
Observer
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Time to Clinical Dryness and Wound Outcomes After Drainless DAA Total Hip Arthroplasty With Standardized Multilayer Symmetric PDS Plus Closure: Bikini Versus Longitudinal Incisions. [PDF]

Orthop Surg
Zhang T, Hou X, Zheng S, Zhai Y, Zhang C, Zhu J, Li Y, Xiao T, Li Y, Xia T, Liu X, Shen J.   +11 more
europepmc   +1 more source

Marketing Samurai 2017 - Daily Observer

, 2017
Daily, Observer
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Evaluating the internal architecture of the postnatal human maxilla across the stages of tooth development and eruption. [PDF]

Surg Radiol Anat
Mhlathi X, Small C, Hutchinson EF.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Morphologic and urodynamic predictors of renal scarring in pediatric neurogenic bladder A cross-sectional study. [PDF]

Can Urol Assoc J
Yayla D, Aydın Z.
europepmc   +1 more source