Results 81 to 90 of about 3,398,903 (291)
Reumatismo, 2017 Velazquez showed to know the entity of thumb osteoarthritis by finely describing it in one of his paintings. The concepts of anatomical damage, loss of strenght, and functional impairment are transmitted to the observer.
J.H. Villafañe +3 more
doaj +1 more source
OBSERVATIONS ON FUNCTIONAL AND ORGANIC DISEASES [PDF]
American Journal of Psychiatryn ...
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Black hole quantum atmosphere for freely falling observers
Physics Letters B, 2019 We analyze Hawking radiation as perceived by a freely-falling observer and try to draw an inference about the region of origin of the Hawking quanta. To do so, first we calculate the energy density from the stress energy tensor, as perceived by a freely ...
Ramit Dey +3 more
doaj +1 more source
Control design and gain-scheduling using observer-based structures [PDF]
, 2012 we present the procedure to compute the observer-based realization of a given controller and a given model. The application of this procedure to a very simple missile model is proposed in the third section to illustrate the interest of observer-based ...
Daniel Alazard, Alazard, Daniel
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
AstronomyThe passage from generic (non-interacting) plasma to cold plasma with dust around a spherically symmetric black hole is newly analytically studied. The configurations are newly written, and the behaviours of the observer are this way spelt out.
Orchidea Maria Lecian
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source