Results 41 to 50 of about 5,844,081 (298)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Abstract 103 | Interdisciplinary approach to diagnosis and treatment of cranio-mandibular dysfunctions

European Journal of Translational Myology
The mandible is a multifunctional organ. A number of authors point out the mutual influence of bite and body posture. This organ is responsible for biting, tearing, and grinding food.
Elena P. Ivanova
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

FONKSİYONEL SINIF III MALOKLÜZYONUN ERKEN DÖNEM TEDAVİSİNDE SINIF III TWİN-BLOK APAREYİNİN ETKİLERİ: OLGU SUNUMU

European Annals of Dental Sciences, 2016
Sınıf III maloklüzyonun erken dönem tedavisi,baş ve yüz bölgesinin normal büyüme ve gelişimi için daha uygun bir ortamın oluşturulması ve normal bir psikososyal gelişim için yüz estetiğinin arttırılması açısından önemlidir.
Gökhan Yüksel, M. Okan Akçam
doaj  

Exploring risk factors for totally implantable venous access devices (TIVADs)-related thrombotic occlusion in the off-treatment period

Scientific Reports, 2023
Totally implantable venous access devices (TIVADs) have been widely used for many years in the management of patients suffering from cancer. Thrombotic occlusion is the most common functional complication in the off-treatment period.
Lei Liu, Zhanlun Liu, Jianxin Wang, Meng Cheng, Yanli Xie, Weina Wang, Cuicui Ma, Lina Zhang, Zhenchuan Song, Yanshou Zhang   +9 more
doaj   +1 more source

Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis.

The Lancet
BACKGROUND Trials of endovascular therapy for basilar artery occlusion, including vertebral occlusion extending into the basilar artery, have shown inconsistent results.
R. Nogueira, T. Jovin, Xinfeng Liu, Wei Hu, L. L. Langezaal, Chuanhui Li, Q. Dai, Chunrong Tao, Francisco Mont’Alverne, Xunming Ji, Rui Liu, Rui Li, D. Dippel, Chuanjie Wu, Wusheng Zhu, Pengfei Xu, W. V. van Zwam, Longfei Wu, Chao Zhang, P. Michel, Jian Chen, Li Wang, Volker Puetz, Wenbo Zhao, Tianlong Liu, Heinrich J. Audebert, Zhongjun Chen, O. Pontes-Neto, Tingyu Yi, Timothy P. Moran, M. Doheim, W. Schonewille   +31 more
semanticscholar   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Endovascular intervention for basilar artery occlusion in the elderly

Therapeutic Advances in Neurological Disorders, 2021
Background: To date, few data have been reported on clinical outcomes following interventions in elderly populations with acute basilar artery occlusion.
Weidong Luo, Wenguo Huang, Min Zhang, Xing Liu, Zhangbao Guo, Peiyang Zhou, Li Wang, Xinmin Fu, Shiquan Yang, Shuai Zhang, Zhiming Zhou, Min Zhang, Junjie Yuan, Shuai Liu, Jiaxing Song, Zhongming Qiu, Hongfei Sang, Fengli Li, Wenjie Zi, Deping Wu, Wenhua Liu, Qingwu Yang   +21 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source