Results 201 to 210 of about 1,317,401 (269)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Time to surgery and postoperative functional outcomes among patients with chronic subdural haematomas. [PDF]

J Neurol Neurosurg Psychiatry
Baig Mirza A, Knight J, Lam PY, Georgiannakis A, Vastani A, Fayez F, Rashed S, Kalaitzoglou D, El Sheikh M, Murphy S, Rampersad N, Goh JJ, Yousaf A, Ahmed R, Ahmed D, Chand R, Parwez R, Goonewardena E, Johani NF, Corr P, Nolan D, Genel O, El-Diaz N, Syrris C, Hassan S, Okasha M, Booth TC, Moran C, Matloob SA, Sanusi TD, Babak A, Sadek AR, Vaqas B, Grahovac G, Lavrador JP.   +34 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Intraoperative motor evoked potentials (MEP) improvement predicts functional outcomes in intracranial surgery. [PDF]

Clin Neurophysiol Pract
Velur P, Gong M, Zada G, Briggs R, Velur V.   +4 more
europepmc   +1 more source

Assessment of pain and functional outcomes after lower limb amputation: a scoping review. [PDF]

BMJ Open
Kim JM, Balthazaar SJT, Alsayed K, Nightingale T, Falla D, Yeo SH, Ding Z.   +6 more
europepmc   +1 more source

The Role of Videoconferencing Teleconsultation in Improving Transfer Efficiency and Functional Outcomes in Rural Stroke Care: Retrospective Cohort Study. [PDF]

JMIR Mhealth Uhealth
Wang CS, Chen YJ, Lin TC, Huang HM, Tu PR, Chen PL, Huang JA.   +6 more
europepmc   +1 more source