Results 111 to 120 of about 1,020,025 (280)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Development of aqueous-based multi-herbal combination using principal component analysis and its functional significance in HepG2 cells

open access: yesBMC Complementary and Alternative Medicine, 2019
Background The present study was carried out to prepare multi-herbal combination via comparing antioxidant activity and polyphenolic composition of five medicinal plant extracts of Punica granatum L., Putranjiva roxburghii Wall., Swertia chirata Buch ...
Pardeep Kaur   +4 more
doaj   +1 more source

CMB Constraints on Principal Components of the Inflaton Potential

open access: yes, 2010
We place functional constraints on the shape of the inflaton potential from the cosmic microwave background through a variant of the generalized slow roll approximation that allows large amplitude, rapidly changing deviations from scale-free conditions ...
Cora Dvorkin, S. M. Leach, Wayne Hu
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Heuristic model in joint EEG-fMRI analysis [PDF]

open access: yes, 2015
This work deals with the joint EEG-fMRI analysis based on the heuristic model. There is described principle of the heuristic model which assumes that the BOLD (blood oxygen level depend) signal measured by fMRI (functional magnetic resonance imaging) is ...
Janeček, D.
core  

Functional linear regression analysis for longitudinal data

open access: yes, 2006
We propose nonparametric methods for functional linear regression which are designed for sparse longitudinal data, where both the predictor and response are functions of a covariate such as time.
Müller, Hans-Georg   +2 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Functional abilities of cultivable plant growth promoting bacteria associated with wheat (Triticum aestivum L.) crops

open access: yesGenetics and Molecular Biology, 2016
In the pursuit of sustainable agriculture, bioinoculants usage as providers of a crop's needs is a method to limit environmental damage. In this study, a collection of cultivable putative plant growth promoting (PGP) bacteria associated with wheat crops ...
Fernanda da S. Moreira   +6 more
doaj   +1 more source

A Dynamic Semiparametric Factor Model for Implied Volatility String Dynamics [PDF]

open access: yes
A primary goal in modelling the implied volatility surface (IVS) for pricing and hedging aims at reducing complexity. For this purpose one fits the IVS each day and applies a principal component analysis using a functional norm.
Enno Mammen   +2 more
core  

Functional linear regression via canonical analysis

open access: yes, 2011
We study regression models for the situation where both dependent and independent variables are square-integrable stochastic processes. Questions concerning the definition and existence of the corresponding functional linear regression models and some ...
He, Guozhong   +3 more
core   +1 more source

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