Results 111 to 120 of about 1,020,465 (280)

Development of aqueous-based multi-herbal combination using principal component analysis and its functional significance in HepG2 cells

open access: yesBMC Complementary and Alternative Medicine, 2019
Background The present study was carried out to prepare multi-herbal combination via comparing antioxidant activity and polyphenolic composition of five medicinal plant extracts of Punica granatum L., Putranjiva roxburghii Wall., Swertia chirata Buch ...
Pardeep Kaur   +4 more
doaj   +1 more source

Heuristic model in joint EEG-fMRI analysis [PDF]

open access: yes, 2015
This work deals with the joint EEG-fMRI analysis based on the heuristic model. There is described principle of the heuristic model which assumes that the BOLD (blood oxygen level depend) signal measured by fMRI (functional magnetic resonance imaging) is ...
Janeček, D.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Principal Nested Spheres for Time Warped Functional Data Analysis [PDF]

open access: yes, 2013
There are often two important types of variation in functional data: the horizontal (or phase) variation and the vertical (or amplitude) variation. These two types of variation have been appropriately separated and modeled through a domain warping method
Lu, Xiaosun, Marron, J. S.
core  

Functional linear regression analysis for longitudinal data

open access: yes, 2006
We propose nonparametric methods for functional linear regression which are designed for sparse longitudinal data, where both the predictor and response are functions of a covariate such as time.
Müller, Hans-Georg   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Functional abilities of cultivable plant growth promoting bacteria associated with wheat (Triticum aestivum L.) crops

open access: yesGenetics and Molecular Biology, 2016
In the pursuit of sustainable agriculture, bioinoculants usage as providers of a crop's needs is a method to limit environmental damage. In this study, a collection of cultivable putative plant growth promoting (PGP) bacteria associated with wheat crops ...
Fernanda da S. Moreira   +6 more
doaj   +1 more source

Liquidity commonality does not imply liquidity resilience commonality: A functional characterisation for ultra-high frequency cross-sectional LOB data

open access: yes, 2014
We present a large-scale study of commonality in liquidity and resilience across assets in an ultra high-frequency (millisecond-timestamped) Limit Order Book (LOB) dataset from a pan-European electronic equity trading facility.
Kosmidis, Ioannis   +2 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A Dynamic Semiparametric Factor Model for Implied Volatility String Dynamics [PDF]

open access: yes
A primary goal in modelling the implied volatility surface (IVS) for pricing and hedging aims at reducing complexity. For this purpose one fits the IVS each day and applies a principal component analysis using a functional norm.
Enno Mammen   +2 more
core  

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