Results 211 to 220 of about 365,137 (249)

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Localized Functional Principal Component Analysis [PDF]

open access: yesJournal of the American Statistical Association, 2015
We propose localized functional principal component analysis (LFPCA), looking for orthogonal basis functions with localized support regions that explain most of the variability of a random process. The LFPCA is formulated as a convex optimization problem through a novel deflated Fantope localization method and is implemented through an efficient ...
Kehui Chen, Jing Lei
exaly   +6 more sources

Multilevel Functional Principal Component Analysis

open access: yesAnnals of Applied Statistics, 2009
Published in at http://dx.doi.org/10.1214/08-AOAS206 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Brian Caffo   +2 more
exaly   +6 more sources
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Supervised functional principal component analysis

Statistics and Computing, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yunlong Nie   +3 more
openaire   +1 more source

Principal Components Analysis of Sampled Functions

Psychometrika, 1986
This paper describes a technique for principal components analysis of data consisting of n functions each observed at p argument values. This problem arises particularly in the analysis of longitudinal data in which some behavior of a number of subjects
Besse, Philippe, Ramsay, J. O.
openaire   +1 more source

Sensitivity analysis in functional principal component analysis

Computational Statistics, 2005
Penalized functional principal components analysis (PCA) is considered. Sensitivity analysis based on the empirical influence functions (EIF) is discussed. EIFs are calculated for a fixed penalty parameter \(\lambda\) and for \(\lambda\) obtained by cross-validation. Cook's distances are proposed for single-case diagnostics.
Yoshihiro Yamanishi, Yutaka Tanaka
openaire   +3 more sources

Principal component analysis of infinite variance functional data

Journal of Multivariate Analysis, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Piotr Kokoszka, Rafal Kulik
openaire   +1 more source

A Wavelet Approach to Functional Principal Component Analysis

1998
The aim of this paper is to approximate the estimates in the principal component analysis of a continuous time stochastic process (functional PCA) by using wavelet methods. A short review of estimating in the functional PCA leads to the problem of solving the integral equation with the covariance function as kernel.
Francisco A. Ocaña   +2 more
openaire   +1 more source

Uncertainty in functional principal component analysis

Journal of Applied Statistics, 2016
ABSTRACTPrincipal component analysis (PCA) and functional principal analysis are key tools in multivariate analysis, in particular modelling yield curves, but little attention is given to questions of uncertainty, neither in the components themselves nor in any derived quantities such as scores.
James Sharpe, Nick Fieller
openaire   +1 more source

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