Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle +11 more
wiley +1 more source
Data-driven frailty and reserve phenotypes in older outpatients: a cluster analysis of complementary geriatric assessment. [PDF]
Belfiori M +5 more
europepmc +1 more source
Structural and functional coupling alterations in autism spectrum disorder with and without comorbid attention deficit hyperactivity disorder. [PDF]
Zhang X, Zhou Y, Hu L, Yan J, Yin X.
europepmc +1 more source
Dimensions of Self-Perceived Functionality in Older Adults Based on the Brazilian National Health Survey. [PDF]
Nascimento JASD +9 more
europepmc +1 more source
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Principal Components Analysis of Sampled Functions
Psychometrika, 1986This paper describes a technique for principal components analysis of data consisting of n functions each observed at p argument values. This problem arises particularly in the analysis of longitudinal data in which some behavior of a number of subjects is measured at a number of points in time.
Besse, Philippe, Ramsay, J. O.
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Supervised functional principal component analysis
Statistics and Computing, 2017zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yunlong Nie +3 more
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Sensitivity analysis in functional principal component analysis
Computational Statistics, 2005Penalized functional principal components analysis (PCA) is considered. Sensitivity analysis based on the empirical influence functions (EIF) is discussed. EIFs are calculated for a fixed penalty parameter \(\lambda\) and for \(\lambda\) obtained by cross-validation. Cook's distances are proposed for single-case diagnostics.
Yamanishi, Yoshihiro, Tanaka, Yutaka
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Uncertainty in functional principal component analysis
Journal of Applied Statistics, 2016ABSTRACTPrincipal component analysis (PCA) and functional principal analysis are key tools in multivariate analysis, in particular modelling yield curves, but little attention is given to questions of uncertainty, neither in the components themselves nor in any derived quantities such as scores.
James Sharpe, Nick Fieller
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Robust Functional Principal Component Analysis
2014When dealing with multivariate data robust principal component analysis (PCA), like classical PCA, searches for directions with maximal dispersion of the data projected on it. Instead of using the variance as a measure of dispersion, a robust scale estimator s n may be used in the maximization problem.
Juan Lucas Bali, Graciela Boente
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