Results 91 to 100 of about 1,002,594 (295)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Novel Technical Parameters-Based Classification of Harvesters Using Principal Component Analysis and Q-Type Cluster Model

Agriculture
The advancement of agricultural mechanization necessitates precise and standardized classification based on technical characteristics to enhance green, efficient, and high-quality development.
Kibiya Abubakar Yusuf, Edwin O. Amisi, Qishuo Ding, Xinxin Chen, Gaoming Xu, Abdulaziz Nuhu Jibril, Moussita G. Gedeon, Zakariya M. Abdulhamid   +7 more
doaj   +1 more source

Functional Analysis of Continuous, High-Resolution Measures in Aging Research: A Demonstration Using Cerebral Oxygenation Data From the Irish Longitudinal Study on Aging

Frontiers in Human Neuroscience, 2020
Background: A shift towards the dynamic measurement of physiologic resilience and improved technology incorporated into experimental paradigms in aging research is producing high-resolution data.
John D. O’Connor, Matthew D. L. O’Connell, Matthew D. L. O’Connell, Roman Romero-Ortuno, Roman Romero-Ortuno, Belinda Hernández, Louise Newman, Richard B. Reilly, Rose Anne Kenny, Silvin P. Knight   +9 more
doaj   +1 more source

FUNCTIONAL PRINCIPAL COMPONENTS MODEL FOR HIGH-DIMENSIONAL BRAIN IMAGING [PDF]

, 2011
We establish a fundamental equivalence between singular value decomposition (SVD) and functional principal components analysis (FPCA) models. The constructive relationship allows to deploy the numerical efficiency of SVD to fully estimate the components ...
Caffo, Brian S, Crainiceanu, Ciprian, Davatzikos, Christos, Schwartz, Brian S., Yousem, David M., Zipunnikov, Vadim   +5 more
core   +1 more source

Functional linear regression via canonical analysis

, 2011
We study regression models for the situation where both dependent and independent variables are square-integrable stochastic processes. Questions concerning the definition and existence of the corresponding functional linear regression models and some ...
He, Guozhong, Müller, Hans-Georg, Wang, Jane-Ling, Yang, Wenjing   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Transgenic Overexpression of LARGE Induces alpha-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle [PDF]

, 2010
Background: LARGE is one of seven putative or demonstrated glycosyltransferase enzymes defective in a common group of muscular dystrophies with reduced glycosylation of alpha-dystroglycan.
Brockington, M, Brown, SC, Cirak, S, Liu, K, Muntoni, F, Sharp, PS, Torelli, S, Wells, DJ   +7 more
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Principal Component Analysis for Functional Data on Riemannian Manifolds and Spheres

, 2017
Functional data analysis on nonlinear manifolds has drawn recent interest. Sphere-valued functional data, which are encountered for example as movement trajectories on the surface of the earth, are an important special case.
Dai, Xiongtao, Müller, Hans-Georg
core  

Minimization of multi-penalty functionals by alternating iterative thresholding and optimal parameter choices [PDF]

, 2014
Inspired by several recent developments in regularization theory, optimization, and signal processing, we present and analyze a numerical approach to multi-penalty regularization in spaces of sparsely represented functions.
Naumova, Valeriya, Peter, Steffen
core   +1 more source