Results 211 to 220 of about 300,116 (259)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Investigating the Genetic and Molecular Basis of Melanin and Edible Quality in <i>Auricularia cornea</i>. [PDF]

J Fungi (Basel)
Cui Y, Yao F, Ma X, Liu T, Sun X, Fang M, Lu L, Zhang Y, Li Y, Chen X, Xu X.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Effect of implant number, attachment type, and framework material on stress distribution in mandibular overdentures: a finite element analysis. [PDF]

BMC Oral Health
Sai̇p S, Yeşi̇l Z.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The primacy of species turnover over intraspecific variation in the environmental filtering of understory ferns. [PDF]

Front Plant Sci
Zhou Y, Zhang Z, Liu H, Jiang S, Zheng Z, Shen G, Wang X, Yang Q.   +7 more
europepmc   +1 more source

Missense mutations on SynGAP C2 domain impair membrane diffusion. [PDF]

Protein Sci
Miotto M, Bo' L, Ruocco G, Di Angelantonio S, Basilico B.   +4 more
europepmc   +1 more source

Cellular mechanisms underlying social regulation of the posterior tubercular nucleus in zebrafish (<i>Danio rerio</i>). [PDF]

Front Neural Circuits
Adams CL, Scott EM, Issa FA.
europepmc   +1 more source

Functional gradient reorganization and transcriptomic signatures underlying 1 Hz rTMS treatment in first-episode schizophrenia following right orbitofrontal cortex stimulation. [PDF]

Neuroimage Clin
Miao W, Jiao X, Zeng N, Wang M, Zhang K, Yang C, Xie Y, Wang Z, Hu Q.   +8 more
europepmc   +1 more source

Immune checkpoint landscape in CD4⁺ T cells stratifies HIV-infected individuals by clinical progression. [PDF]

Immunol Res
Spampinato S, Scuderi G, Di Rosa M, Fagone P, Nunnari G.   +4 more
europepmc   +1 more source