Results 141 to 150 of about 11,002,643 (373)
Decomposition principle for linear fractional functional programs [PDF]
Suresh Chandra
openalex +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Language Support for Generic Programming in Object-Oriented Languages: Design Challenges
It is generally considered that object-oriented (OO) languages provide weaker support for generic programming (GP) as compared with functional languages such as Haskell or SML. There were several comparative studies which showed this. But many new object-
Julia Belyakova
doaj +1 more source
Functional Programming and Planning for the Operating Suite, Location, Traffic Flow, Supply Lines [PDF]
Gordon A. Friesen
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NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
A Metamodel of Unit Testing for Object-Oriented Programming Languages [PDF]
A unit test is a method for verifying the accuracy and the proper functioning of a portion of a program. This work consists to study the relation and the approaches to test Object-Oriented Programming (OOP) programs and to propose a metamodel that enables the programmer to write the tests while writing the source code to be tested by exploiting the key
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Functional Programming Using the New C++ Standard
Today software technology evolves very quickly, to an old paradigm, called functional programming. This paradigm uses lambda functions ready to be used where declared instead of function pointers.
Radu Bucea-Manea-Tonis+1 more
doaj
Performance Evaluation of a Hybrid Programming Model for RSDFT on T2K Open Supercomputer
Non-uniform memory access (NUMA) systems, where each processor has its own memory, have been popular platform in high-end computing. While some early studies had reported that a flat-MPI programming model outperformed an OpenMP/MPI hybrid programming ...
Miwako Tsuji, Mitsuhisa Sato
doaj +1 more source