Results 51 to 60 of about 121,983 (302)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

A Comparison of Functional and Imperative Programming Techniques for Mathematical Software Development [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2014
Functional programming has traditionally been considered elegant and powerful, but also somewhat impractical for ordinary computing. Proponents of functional programming claim that the evolution of functional languages makes their use feasible in many ...
Scott Frame, John W. Coffey
doaj  

On representation of simulation time in functional programming style

open access: yesТруды Института системного программирования РАН, 2019
Functional programming plays the big role in the modern computer science and its importance is growing. This is not accidential: this approach helps to create better and more reliable software that is easy to reason about (both manually and automatically)
D. V. Buzdalov   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Smart Contract Design Pattern for Processing Logically Coherent Transaction Types

open access: yesApplied Sciences
Recent research shows that the source code of smart contracts is often cloned. The processing of related types of transactions in blockchain networks results in the implementation of many similar smart contracts.
Tomasz Górski
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

ECOLE: a pedagogical environment for non procedural languages

open access: yesJournal of Computer Science and Technology, 2007
The work described in this paper is related to three areas in the programming world : logic, functional and object programming. The main objective is essentially pedagogical since it is question here to make a synthesis on non procedural languages.
D. E. Zegour, W. K. Hidouci
doaj  

Functional Data Science for Secondary-School Students

open access: yesInformatics in Education
CODAP is a widely-used programming environment for secondary school data science. Its direct-manipulation–based design offers many advantages to learners, especially younger students.
Paul Biberstein   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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