Results 61 to 70 of about 121,983 (302)

A Brief Overview of the Pawns Programming Language

open access: yesSoftware
This paper describes the Pawns programming language, currently under development, which uses several novel features to combine the functional and imperative programming paradigms.
Lee Naish
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

A Scientific Calculator for Exact Real Number Computation Based on LRT, GMP and FC++

open access: yesActa Universitaria, 2012
Language for Redundant Test (LRT) is a programming language for exact real number computation. Its lazy evaluation mechanism (also called call-by-need) and its infinite list requirement, make the language appropriate to be implemented in a functional ...
J. A. Hernández   +2 more
doaj  

Types of mathematical thinking implemented in the learn process of functional programming

open access: yesTecnura, 2018
Context: This article presents and analyzes the results of a research carried out in a classroom, in the context of the learning of functional programming at university level in Systems Engineering and Computing program, from the application of the types
Omar Iván Trejos Buriticá
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Formation of cloud-based learning environment for professional training in programming

open access: yesCTE Workshop Proceedings, 2014
The article is devoted the question of forming a full functional based on cloud technology to study subjects from programming cycle for specialists in programming. The object of the research – the process applying cloud technologies in learning.
N. A. Kharadzjan
doaj   +1 more source

Implementation of ERP system functionalities for data acquisition based on API at the study program of Universities

open access: diamond, 2021
Kholiq Budiman   +5 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

3D Dynamic Programming Approach to Functional Equations with Applications

open access: yesJournal of Function Spaces, 2020
This article demonstrates the graphical existence of a single fixed point while imposing the contractive condition of Chatterjea type F-contraction on F-metric space (briefly as F-MS). We present two examples that verify the validity of the results given
Awais Asif   +4 more
doaj   +1 more source

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