Results 71 to 80 of about 121,983 (302)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Influence of Birth Weight on the Renal Development and Kidney Diseases in Adulthood: Experimental and Clinical Evidence

International Journal of Nephrology, 2012
Several clinical and experimental studies support the hypothesis that foetal programming is an important determinant of nephropathy, hypertension, coronary heart disease, and type 2 diabetes during adulthood.
Maria C. P. Franco, Vanessa Oliveira, Beatriz Ponzio, Marina Rangel, Zaira Palomino, Frida Zaladek Gil   +5 more
doaj   +1 more source

Analyzing structural and functional brain changes related to an integrative cognitive remediation program for schizophrenia: A randomized controlled trial

, 2023
Agurne Sampedro, Naroa Ibarretxe‐Bilbao, Javier Peña, Alberto Cabrera‐Zubizarreta, Pedro Sánchez, Ainara Gómez‐Gastiasoro, Nagore Iriarte‐Yoller, Cristobal Pavón, Mikel Tous‐Espelosin, Natalia Ojeda   +9 more
openalex   +1 more source

Programming Diffusion and Localization of DNA Signals in 3D‐Printed DNA‐Functionalized Hydrogels [PDF]

, 2020
Julia Müller, Anna C. Jäkel, Dominic Schwarz, Lukas Aufinger, Friedrich C. Simmel   +4 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Transforming Functional Logic Programs into Monadic Functional Programs [PDF]

, 2011
We present a high-level transformation scheme to translate lazy functional logic programs into pure Haskell programs. This transformation is based on a recent proposal to efficiently implement lazy non-deterministic computations in Haskell in a monadic style.
Bernd Braßel, Sebastian Fischer, Michael Hanus, Fabian Reck   +3 more
openaire   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Linear and undulating resistance training programming induce similar outcomes on physical fitness in elderly women

Revista Brasileira de Cineantropometria e Desempenho Humano
The aim of the present study was to analyze the effect of two different types of resistance training programming (linear and daily undulating) on submaximal strength and functional capacity in elderly women.
Surama do Carmo Souza da Silva, Flavio de Oliveira Pires, Marifran Tomé Batista Junior, Larissa de Lourdes Padilha Serra, Carlos Brendo Ferreira Reis, Leudyenne Pacheco de Abreu, Paula Tâmara Vieira Teixeira Pereira, Christian Emmanuel Torres Cabido, Richard Diego Leite   +8 more
doaj   +1 more source