Results 71 to 80 of about 681,398 (337)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
ECOLE: a pedagogical environment for non procedural languages
Journal of Computer Science and Technology, 2007 The work described in this paper is related to three areas in the programming world : logic, functional and object programming. The main objective is essentially pedagogical since it is question here to make a synthesis on non procedural languages.
D. E. Zegour, W. K. Hidouci
doaj
From Principles to Practice with Class in the First Year [PDF]
Electronic Proceedings in Theoretical Computer Science, 2013 We propose a bridge between functional and object-oriented programming in the first-year curriculum. Traditionally, curricula that begin with functional programming transition to a professional, usually object-oriented, language in the second course ...
Sam Tobin-Hochstadt, David Van Horn
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Comparison of Functional and Imperative Programming Techniques for Mathematical Software Development [PDF]
Journal of Systemics, Cybernetics and Informatics, 2014 Functional programming has traditionally been considered elegant and powerful, but also somewhat impractical for ordinary computing. Proponents of functional programming claim that the evolution of functional languages makes their use feasible in many ...
Scott Frame, John W. Coffey
doaj
On representation of simulation time in functional programming style
Труды Института системного программирования РАН, 2019 Functional programming plays the big role in the modern computer science and its importance is growing. This is not accidential: this approach helps to create better and more reliable software that is easy to reason about (both manually and automatically)
D. V. Buzdalov +2 more
doaj +1 more source
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Smart Contract Design Pattern for Processing Logically Coherent Transaction Types
Applied SciencesRecent research shows that the source code of smart contracts is often cloned. The processing of related types of transactions in blockchain networks results in the implementation of many similar smart contracts.
Tomasz Górski
doaj +1 more source
A Purely Functional Computer Algebra System Embedded in Haskell
, 2018 We demonstrate how methods in Functional Programming can be used to implement a computer algebra system. As a proof-of-concept, we present the computational-algebra package.
G-M Greuel +5 more
core +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source