Results 181 to 190 of about 15,977,825 (398)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

FUNCTIONAL PROPERTIES OF TENDON RECEPTORS IN THE FROG

, 1968
Fumio Ito
openalex   +2 more sources

Effects of Glyceraldehyde on the Structural and Functional Properties of Sickle Erythrocytes [PDF]

, 1978
Alan M. Nigen, James M. Manning
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

An Isolation Procedure for the Native alpha Chain of Bovine Hemoglobin. A Study of the Functional Properties of This Chain and Its Hybrid with the Human beta Chain [PDF]

, 1977
Simon H. de Bruin, J. J. M. Joordens, Harry S. Rollema   +2 more
openalex   +1 more source

Bioactive food derived peptides: a review on correlation between structure of bioactive peptides and their functional properties

Journal of food science and technology, 2019
Z. Karami, B. Akbari‐adergani
semanticscholar   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Studies on the Relations between Molecular and Functional Properties of Hemoglobin

, 1968
Eraldo Antonini, Maurizio Brunori, S. G. Anderson   +2 more
openalex   +1 more source

The Functional and Fluorescence Properties of Escherichia coli RNA Polymerase Reacted with Fluorescamine [PDF]

, 1977
Sándor Damjanovich, Wolfgang Bähr, Thomas M. Jovin   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source