Results 71 to 80 of about 1,610,238 (288)
FRUIT: Fuzzy Representation of Unbounded and Imprecise Terms in Non-Functional Requirements
IEEE AccessIt is challenging to verify Non-Functional Requirements (NFRs) because the traditional verification process typically uses the binary concept of true or false to determine whether a requirement has been fulfilled, leaving no space for uncertainty, even ...
Franklin Parrales-Bravo +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
مجله انفورماتیک سلامت و زیست پزشکی, 2019 Introduction: In the field of studying information systems, qualitative approach is one of the ways to extract the system requirements from the perspective of the users.
Zahra Mahmoudzadeh Sagheb +4 more
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
IEEE Access, 2019 The architecture of modern automotive electronic systems is composed of multiple distributed mixed-criticality functions. The effective utilization of such systems with heterogeneity is hindered by the scheduling of multifunctions.
Yan Liu +3 more
doaj +1 more source
, 2010 In a recent paper it was shown how quark scattering in a quenched, eikonal model led to a momentum-transfer dependent amplitude expressed in terms of Halpern's functional integral; and how the requirement of manifest gauge invariance converted that ...
Fried, H. M. +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Active reservoir management: a model solution [PDF]
, 1992 Steady-state procedures, of their very nature, cannot deal with dynamic situations. Statistical models require extensive calibration, and predictions often have to be made for environmental conditions which are often outside the original calibration ...
Hilton, J., Irish, A.E., Reynolds, C.S.
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source