Results 201 to 210 of about 566,644 (262)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Heuristic multi-site optimization for protein sequence design using Masked Protein Language Models. [PDF]

PLoS Comput Biol
Wang L, Wang Y, Qiu C, Xiao L, Liu X, Chen J.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Artificial intelligence in orthopedic regenerative medicine: from design to clinical translational pathways. [PDF]

Front Cell Dev Biol
Xu T, Chen W, Chai Y, Hong J, Wu Y, Xu Y, Qiu S, Luo Q.   +7 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Challenges and opportunities in designing innovative emergency-evacuation equipment for bed-dependent hospital patients: a scoping review with a focus on evacuation mattresses and stretchers. [PDF]

BMC Emerg Med
Fattahipour R, Teymouri F, Sharififar S, Khankeh HR, Azizi M.   +4 more
europepmc   +1 more source

Prosthetic maintenance profiles and functional performance of single-implant mandibular overdentures in geriatric edentulism: A prospective clinical evaluation. [PDF]

Bioinformation
Kaur D, Kaur R, Garg M, Mansuri S, Patel R, K V R, Tiwari R, M C P.   +7 more
europepmc   +1 more source

Human Islet. [PDF]

Cell Prolif
Zou J, Li S, Fu H, Zhang M, Hu A, Tian X, Du Y, Wei L, Chen X, Gao J, Liang R, Feng X, Li Y, Wang Y, Cai X, Sun P, Ding X, Zhang B, Liu T, Liu N, Hao J, Wang L, Zhao H, Cao J, Ma A, Zhu L, Li Q, Wei Q, Ding X, Cheng Y, Zhao T, Wang S.   +31 more
europepmc   +1 more source

Correction: Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first responder, highly connected ("hub"), and leader beta-cells. [PDF]

Front Endocrinol (Lausanne)
Frontiers Production Office.
europepmc   +1 more source

From prototype to deployment: An EU-centric lifecycle framework for law enforcement AI. [PDF]

Open Res Eur
Aramburu M, García J, Gaines S, Touleimat N, La Mattina E, Akhgar B, Kavallieros D.   +6 more
europepmc   +1 more source