Results 161 to 170 of about 107,010 (279)

Understanding of Consciousness in Absence Seizures: A Literature Review

Emilie Groulx-Boivin,1,2 Tasha Bouchet,3 Kenneth A Myers1,2,4 1Department of Neurology and Neurosurgery, Montreal Children’s Hospital, McGill University, Montreal, Quebec, Canada; 2Department of Pediatrics, Montreal Children’s Hospital, McGill University,
Groulx-Boivin E, Bouchet T, Myers KA
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Long and Winding Road: Diagnostic Delays in Functional Seizures. [PDF]

Epilepsy Curr
Terman SW.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Quantifying the impact of a computer-aided diagnostic score on the clinical diagnosis of functional seizures. [PDF]

Epilepsia
Kerr WT, McFarlane KN, Allas CH, Terman SW, Reuber M, Seo SH, Seo SH, Barnard P, Koek AY, Karimi AH, Sreenivasan SS, Grauer JS, Sun D, Watson M, Patterson EH, Castellano J, Bagić AI, Hickman LB, Kutschman KH, Knowles L, Wardrope A, Ostwal P, MacDonald BK, Berry M, Reddy L, Robinson-Mayer N, Beimer NJ, Reddy R, Yaghoubi SK, Kirkpatrick LA, Carns DR, Israel AJ, Feusner JD, Xia Z, Wang Y, Strom LA, Pennell PB, Stern JM, Hadjiiski L, Stacey WC.   +39 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Semiological differences of functional seizures between pediatrics and adults: video electroencephalography analysis. [PDF]

Acta Epileptol
Al-Azayem SA, Kishk NA, Magdy R, Nawito A, Elsebaie EH, Belal M, Elelwany DA.   +6 more
europepmc   +1 more source

Are brain MRI abnormalities associated with the semiology of functional seizures? [PDF]

Brain Behav, 2023
Asadi-Pooya AA, Kerr WT, Karakis I, Kanemoto K, Daza-Restrepo A, Farazdaghi M, Horbatch FJ, Beimer NJ, Eliashiv DE, Risman A, Sugimoto Y, Giagante B.   +11 more
europepmc   +1 more source