Results 71 to 80 of about 687,881 (263)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Spatial and functional heterogeneities shape collective behavior of tumor-immune networks.

open access: yesPLoS Computational Biology, 2015
Tumor growth involves a dynamic interplay between cancer cells and host cells, which collectively form a tumor microenvironmental network that either suppresses or promotes tumor growth under different conditions. The transition from tumor suppression to
Daniel K Wells   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Phylogeny and Functional Traits Jointly Shape Global Rice Pest Invasions

open access: yesInsects
Biological invasions by crop pests increasingly threaten global food security, yet the mechanisms underlying invasion success remain poorly understood, particularly within focal crop systems.
Jiayuan Xie   +4 more
doaj   +1 more source

Universal Shape of Scaling Functions in Turbulence

open access: yesPhysical Review Letters, 1995
Using a novel device that enables the real-time measurement of high-order structure functions in turbulence with superior statistical accuracy, we study the shape of the structure function at scales where it is influenced by viscosity. The experiments on a variety of laboratory turbulent flows demonstrate that this shape is universal.
Herweijer, J.A., Water, van de, W.
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Bioenergy cropping systems shape ant community composition and functional roles

open access: yesFrontiers in Conservation Science
The adoption of biomass crops grown for energy is a likely source of major landscape change in coming decades during the transition from fossil fuels.
Nathan L. Haan   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Functional Morphology Studies on the Cuticle of Spherical Shape Beetles

open access: yesProceedings
Most insects have an elongated shape and can be divided into two main geometric sides: the dorsal and the ventral [...]
Yuanyuan Lu
doaj   +1 more source

Minimization of the energy in metal forming process of the cylindric shape tool through punch shape changes

open access: yesComputer Assisted Methods in Engineering and Science, 2023
In this paper the sensitivity based optimization problem is considered. The shape of the first of two contacting bodies is optimized on the basis of sensitivities calculated for the second body i.e. workpiece.
Włodzimierz Sosnowski   +1 more
doaj  

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