Results 91 to 100 of about 1,657,673 (293)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Predictive Modeling of Functional and Physical Properties of Extrusion Cooked Ready-To-Eat Corn Meal

open access: yesFood ScienTech Journal
Cornmeal is the product of corn-based food processed or pre-cooked through extrusion to produce a ready-to-eat breakfast. The quality of the meal depends on the extrusion cooking factors and process variables.
Adeyemi Adio Aderele   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ANALYSIS OF THERMAL DECOMPOSITION KINETICS AND THERMAL HAZARD ASSESSMENT OF NITROBENZOIC ACID ISOMERS BY DSC AND THERMOGRAVIMETRIC METHOD [PDF]

open access: yesQuímica Nova
Nitroaromatic acids, ubiquitous intermediates in nitro compounds, find broad applications in pharmaceuticals and fine chemical industries, yet their safety often receives inadequate attention.
Xin Yi Li   +4 more
doaj   +1 more source

Functional principal component analysis as a new methodology for the analysis of the impact of two rehabilitation protocols in functional recovery after stroke

open access: yesJournal of NeuroEngineering and Rehabilitation, 2014
This study addressed the problem of evaluating the effectiveness of two protocols of physiotherapy for functional recovery after stroke. In particular, the study explored the use of Functional Principal Component Analysis (FPCA), a multivariate data ...
M. Sánchez-Sánchez   +7 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Central Limit Theorem for Conditional Mode in the Single Functional Index Model with Data Missing at Random

open access: yesEkonometria
This paper concentrates on nonparametrically estimating the conditional density function and conditional mode within the single functional index model for independent data, particularly when the variable of interest is affected by randomly missing data ...
Anis Allal, Abdessamad Dib, Abbes Rabhi
doaj  

Boundary String Field Theory of the DDbar System

open access: yes, 2000
We develop the boundary string field theory approach to tachyon condensation on the DDbar system. Particular attention is paid to the gauge fields, which combine with the tachyons in a natural way. We derive the RR-couplings of the system and express the
A. A. Gerasimov   +49 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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