The 9+ month marathon: How pregnancy may have shaped human endurance capacities
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
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One Ostium, Three Coronary Arteries: A Rare Coronary Anomaly in a Patient With Secundum Atrial Septal Defect. [PDF]
Joseph A +3 more
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Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
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Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
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Pvr and Pvf2 Are Essential for Valve Cell Differentiation in the Larval Drosophila Heart. [PDF]
Meyer H, Meyer C, Priess B, Paululat A.
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Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
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Systematic Echocardiographic Assessment of the Univentricular Heart Across the Stages of Fontan Palliation: A Practical Guide with Focus on Emerging 3D and 4D Imaging Modalities and Thromboembolic Complications from AEPC Imaging Working Group. [PDF]
Cantinotti M +14 more
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Methodological Challenges for Ablation of BMPR1A in Hypothalamic Tanycytes-A Cautionary Tale. [PDF]
Tao T +3 more
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Comparison of pulmonary ventilation/perfusion tomography and conventional diagnostic techniques in the diagnosis of pulmonary thromboembolism. [PDF]
Lv X, Du F, Fang J.
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A Metabolomics Roadmap to Right Ventricular Function in Pulmonary Hypertension. [PDF]
Pi H, Gharib SA, Leary PJ.
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