Results 141 to 150 of about 140,548 (311)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The Functional Style of Journalism in School?
, 2000 The author discusses the conception of the functional style of journalism (FSJ) in Czech stylistics of the 1990’s, and its application in an educational environment.
Šebesta, Karel
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Abstract Teaching of Image Synthesis in Functional Style
, 2008 We have taught the 3D modelling and image synthesis for computer science students (Master level), exploiting very intensely the functional style of programming/scene description.
core
A remark on minimization of an energy type functional
Le Matematiche, 1993 We study the problem of the minimization of the energy type functional Φ(f)=∫Ω f G f on a class of function with prescribed distribution function that we denote by C(f0).
Adele Ferone
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
, 2012 textDespite being ubiquitous within the Classical style, pedals have received little attention in the scholarly literature. This dissertation adopts a form-functional approach to understanding them with an eye toward distinguishing their normative and ...
Johnston, Sean F.
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Individual style of Dan Brown: functional approach
, 2018 Міжнародне виданняУ статті аналізуються підходи науковців до визначення терміну «ідіостиль». Ідіостиль ро-зглядається як сукупність мовних і стилістичних особливостей, властивих мові певного письменника.
Pindosova T.S. +2 more
core