Results 101 to 110 of about 6,065,144 (355)

Taxonomic and functional trait diversity of wild bees in different urban settings

open access: yesPeerJ, 2017
Urbanization is one of the major anthropogenic processes contributing to local habitat loss and extirpation of numerous species, including wild bees, the most widespread pollinators. Little is known about the mechanisms through which urbanization impacts
É. Normandin   +3 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Molecular physiology of banana fruit ripening : improvement of fruit quality [PDF]

open access: yes, 2008
It is now assumed that the quality of fruit is a complex trait in which a lot of mechanisms are involved, some of them being antagonistic. All of these mechanisms are the results the coercive action of differentially regulated genes.
Mbéguié-A-Mbéguié, Didier
core  

Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation. [PDF]

open access: yes, 2013
An evolutionary response to selection requires genetic variation; however, even if it exists, then the genetic details of the variation can constrain adaptation.
Easlon, Hsien M   +9 more
core   +1 more source

Functional trait evolution in Sphagnum peat mosses and its relationship to niche construction.

open access: yesNew Phytologist, 2019
Species in the genus Sphagnum create, maintain, and dominate boreal peatlands through 'extended phenotypes' that allow these organisms to engineer peatland ecosystems and thereby impact global biogeochemical cycles.
Bryan T. Piatkowski, A. Shaw
semanticscholar   +1 more source

Progressing from ‘functional’ to mechanistic traits [PDF]

open access: yesNew Phytologist, 2017
This article is a Commentary on Larter et al., 215: 97–112.
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

How planktonic microcrustaceans respond to environment and affect ecosystem: a functional trait perspective

open access: yesInternational Aquatic Research, 2019
Functional traits are ecologically relevant characteristics of species. They are relevant to community structuring in face of environmental drivers (response traits) and to ecosystem processes (effect traits).
E. O. Sodré, R. Bozelli
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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