Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
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From "physical repair" to "mental resonance": spatial perception and behavioral reshaping pathways in the renewal of lost under-bridge spaces. [PDF]
Xu Y, Zhang Y, Zhan X.
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Preparation, modification, and characterization of biochar from woodchips and its application in stream water filtration, evaluated through physicochemical and microbiological analyses. Abstract Global microbial water contamination affects 1.8 billion people, necessitating efficient and sustainable treatment methods.
Tariq Khalil +8 more
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Burden of functional difficulties among children aged 2-17 years in Somalia: analysis of a 2022 nationally representative survey data. [PDF]
Ahmed HA +3 more
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A partial envelope approach for modelling multivariate spatial‐temporal data
Abstract In the new era of big data, modelling multivariate spatial‐temporal data is a challenging task due to both the high dimensionality of the features and complex associations among the responses across different locations and time points.
Reisa Widjaja +3 more
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Biomimetic Planning and Design of Five-Minute Living Circle Residential Areas Inspired by Cellular Structure. [PDF]
Pei P, Wang Y, Xia F, Wang Y, Wei Y.
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A conversation with James V. Zidek
AbstractThis article documents a series of exchanges between the authors and the senior Canadian statistician Jim Zidek in early 2026. The interview traces his life trajectory, surveying his principal contributions to statistics while offering insights into his motivations, successes, and challenges. Zidek is a Fellow of the Royal Society of Canada and
Christian Genest, Nancy E. Heckman
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Mechanisms Driving Ground-Dwelling Animal Diversity Responses to Urbanization Gradients: A Case Study From the Chuhe River Riparian Zone in Nanjing, China. [PDF]
Chen W, Zhu Q, Yang Y.
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Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe +2 more
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Spatial Heterogeneity of Phytoplankton Taxa and Functional Groups Under Multidimensional Environmental Factors in Karst Urban Rivers. [PDF]
Wu T +6 more
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