Results 111 to 120 of about 791,940 (315)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Fixed Point Theory and the Ulam Stability

Journal of Function Spaces, 2014
The fixed point method has been applied for the first time, in proving the stability results for functional equations, by Baker (1991); he used a variant of Banach's fixed point theorem to obtain the stability of a functional equation in a single ...
Janusz Brzdęk, Liviu Cădariu, Krzysztof Ciepliński   +2 more
doaj   +1 more source

Variable selection for functional density trees

, 2012
[[abstract]]In this paper, the exhaustive search principle used in functional trees for classifying densities is shown to select variables with more split points. A new variable selection scheme is proposed to correct this bias.
Kuo, SF;Shih, YS
core   +1 more source

The numerical solution of forward–backward differential equations: Decomposition and related issues [PDF]

, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in Journal of Computational and Applied Mathematics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Ford, Neville J., Lumb, Patricia M., Lima, Pedro M., Teodoro, M. Filomena   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Blowup and Global Solutions of a Fourth-Order Parabolic Equation With Variable Exponent Logarithmic Nonlinearity

Journal of Function Spaces
In this work, we deal with a fourth-order parabolic equation with variable exponent logarithmic nonlinearity. We obtain the global existence and blowup solutions using the energy functional and potential well method.
Gülistan Butakın, Erhan Pişkin, Ercan Çelik   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Splitting methods with variable metric for KL functions

, 2014
We study the convergence of general abstract descent methods applied to a lower semicontinuous nonconvex function f that satisfies the Kurdyka-Lojasiewicz inequality in a Hilbert space. We prove that any precompact sequence converges to a critical point of f and obtain new convergence rates both for the values and the iterates.
Frankel, Pierre, Garrigos, Guillaume, Peypouquet, Juan   +2 more
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The analysis of the method on the one variable function’s limit [PDF]

Proceedings of the 2015 International Conference on Advances in Mechanical Engineering and Industrial Informatics, 2015
The limit of one variable function is an important problem in Higher Mathematics, it is a basic method to study the relationship between the function of variables. This template describes some important method about counting the limit, and gives the solving skills.
openaire   +1 more source