Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Use of Functionally Graded Material to Decrease Maximum Temperature of a Coating-Substrate System. [PDF]
Materials (Basel), 2023 Yevtushenko A, Topczewska K, Zamojski P.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Synthesis and Characterization of a Titanium-Based Functionally Graded Material-Structured Biocomposite using Powder Metallurgy. [PDF]
ACS Omega, 2023 Ul Haq E +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Metal Based Functionally Graded Materials [PDF]
, 2010 The aim of this Ebook is to provide a comprehensive overview of the basic production techniques for manufacturing of metal-based graded materials. A concise description of experimental methods and short analysis of some specific structures obtained are presented.
openaire +2 more sources
In Vivo and In Vitro Analyses of Titanium-Hydroxyapatite Functionally Graded Material for Dental Implants. [PDF]
Biomed Res Int, 2021 Wang X, Wan C, Feng X, Zhao F, Wang H.
europepmc +1 more source
Journal of Materials Research and TechnologyThe increasing demands for materials that service under high temperature environments in advanced aero-engines with high thrust-to-weight ratios have led to the exploration of functionally graded materials, which can offer unique advantages for ...
Yaguang Wang +9 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Effect of Functionally Graded Material (FGM) Interlayer in Metal Additive Manufacturing of Inconel-Stainless Bimetallic Structure by Laser Melting Deposition (LMD) and Wire Arc Additive Manufacturing (WAAM). [PDF]
Materials (Basel), 2023 Yoo SW, Lee CM, Kim DH.
europepmc +1 more source