Results 51 to 60 of about 5,255,589 (252)
The paper deals with evaluation of single and multilayer layer PVD coatings based on Cr and Ti widely used in tool application. Additionally, W and WN based coating which are not so widespread were designed and deposited as functionally graded material ...
Jakub Horník +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The design of metal matrix composites can be enhanced by integrating the concept of functionally graded materials (FGM) to produce engineering materials with tailored contradictory properties that suit multifunctioning components.
I.M. El-Galy, M.H. Ahmed, B.I. Bassiouny
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A quasi-3D theory for vibration and buckling of functionally graded sandwich beams [PDF]
This paper presents a finite element model for free vibration and buckling analyses of functionally graded (FG) sandwich beams by using a quasi-3D theory in which both shear deformation and thickness stretching effects are included.
Thai, Huu-Tai +4 more
core +1 more source
For multi-materials having different compositions, delamination or crack may occur at the interface of two dissimilar materials due to differences in a lattice structure, residual thermal stress, and coefficient of thermal expansion.
Seung Weon Yang +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Group and Phase Velocity of Love Waves Propagating in Elastic Functionally Graded Materials
This paper presents a theoretical study of the propagation behaviour of surface Love waves in nonhomogeneous functionally graded elastic materials, which is a vital problem in acoustics.
Piotr KIEŁCZYŃSKI +3 more
doaj +1 more source

