Results 41 to 50 of about 2,484 (261)

Vibration Analysis of Different Types of Porous FG Conical Sandwich Shells in Various Thermal Surroundings [PDF]

Journal of Applied and Computational Mechanics, 2020
Vibration behavior of different types of porous functionally graded (FG) conical sandwich shells are investigated based on a modified high order sandwich shells theory for the first time. Sandwich shell includes FG face sheets covering a homogeneous core
Mohsen Rahmani, Younes Mohammadi, Farshad Kakavand, Hamed Raeisifard   +3 more
doaj   +1 more source

A Time-Domain Solution Method for the Vibration Performance of Viscoelastic Functionally Graded Porous Beams

Vibration
The viscoelastic behavior of functionally graded (FG) materials significantly affects their vibration performance, making it necessary to establish theoretical analysis methods.
Yuhua Cui, Tao Zeng, Yipeng Yang, Xiaohong Wang, Guodong Xu, Su Cheng   +5 more
doaj   +1 more source

Gyroid-based functionally graded porous titanium scaffolds for dental application: Design, simulation and characterizations

Materials & Design, 2022
To improve the mechanical compatibility and biocompatibility of porous scaffolds for dental application, functionally graded porous titanium scaffolds with average porosity of 20–80 % were designed and fabricated by selective laser melting.
Wei Xu, Aihua Yu, Yu Jiang, Yageng Li, Ce Zhang, Harsh-preet Singh, Bowen Liu, Chenjin Hou, Yun Zhang, Shiwei Tian, Jiazhen Zhang, Xin Lu   +11 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Mechanical behavior of 2D FGP beam with uneven porosity distribution

Journal of Architectural and Engineering Research, 2023
This study gives the mechanical behavior of 2D functionally graded porous (FGP) beams using the finite element method. The Matlab code with simple Timoshenko beam elements is written to solve 2D FGP beam problems under distributed load.
Lan Hoang That Ton
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Vibrations Evaluation of Functionally Graded Porous Beams in Thermal Surroundings by Generalized Differential Quadrature Method

Shock and Vibration, 2022
This study investigates how to obtain the natural frequency of functionally graded porous beams simply supported on an elastic substrate in thermal surroundings by the theory of third-order shear deformation.
Mahdi Khakpour, Yousef Bazargan-Lari, Parham Zahedinejad, Mohammad- Javad Kazemzadeh-parsi   +3 more
doaj   +1 more source

Research on the mechanical behaviour of functionally graded porous sandwich plates using a new C1 finite element procedure

Results in Engineering, 2023
This article develops a new C1 rectangular element based on Shi's third-order shear deformation plate theory (TSDT) for the static and dynamic analysis of functionally graded porous (FGP) sandwich plates.
Thanh Hung Nguyen, Truong Thanh Nguyen, Trung Thanh Tran, Quoc-Hoa Pham   +3 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source