Results 91 to 100 of about 1,556,466 (314)

Synergistic effects of organic carbon and silica in preserving structural stability of drying soils

Scientific Reports
Predicted climate warming and prolonged droughts pose a threat to the soil structure as organic carbon losses weaken the stability of soil aggregates.
Luis Alfredo Pires Barbosa, Mathias Stein, Horst H. Gerke, Jörg Schaller   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Another step closer to measuring the ghosts in the nursery: preliminary validation of the Trauma Reflective Functioning Scale

, 2014
The aim of this study was to examine preliminary evidence of the validity of the Trauma Reflective Functioning Scale and to investigate reflective functioning (RF) and attachment in pregnant women with histories of trauma, with a particular focus on the ...
Berthelot, N, Fonagy, P, Odette eBernazzani, Peter eFonagy, Normandin, L, Nicolas eBerthelot, Karin eEnsink, Nicolas Berthelot, Ensink, K, Peter Fonagy, Lina Normandin, Bernazzani, O, Lina eNormandin, Karin Ensink, Odette Bernazzani   +14 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Development of a capability framework for Allied Health research careers in health services

BMC Health Services Research
Background Engaging health services in research is important for ensuring a strong practice-relevant evidence base. To achieve this, health service staff must be equipped with the necessary research capabilities.
Caitlin Brandenburg, Elizabeth C. Ward, Susan Stoikov, Rachelle Pitt, Liza-Jane McBride   +4 more
doaj   +1 more source

Exploring differential item functioning in the SF-36 by demographic, clinical, psychological and social factors in an osteoarthritis population [PDF]

, 2013
The SF-36 is a very commonly used generic measure of health outcome in osteoarthritis (OA). An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items work in the same way across subgroup of a ...
Marie Johnston, Johnston, Marie, Pollard, Beth, Dixon, Diane, Beth Pollard, Diane Dixon   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The role of cognitive functioning within the homeless population

, 2014
Few studies have investigated cognitive functioning within the homeless population but it has been recognised as asignificant difficulty within this group.
Dowling, Noreen
core  

A new method for detecting differential item functioning in the Rasch model [PDF]

, 2010
Differential item functioning (DIF) can lead to an unfair advantage or disadvantage for certain subgroups in educational and psychological testing. Therefore, a variety of statistical methods has been suggested for detecting DIF in the Rasch model.
Zeileis, Achim, Kopf, Julia, Strobl, Carolin   +2 more
core   +1 more source

On the Function of Function

Music Theory Online, 1995
The concept of harmonic function, far from carrying a unitary and universally understood meaning, has signified many different things to theorists past and present. This essay examines some of the different meanings commonly associated with the term today, as well as aspects of the harmonic theories of Rameau, Weber, and ...
openaire   +1 more source