Results 131 to 140 of about 426,019 (285)
Monitoring resources in function-as-a-service platforms
, 2023 Functions deployed in Function-as-Service (FaaS) platforms need to be monitored regarding resource consumption, errors, and application-specific metrics. Platforms like Google Cloud Functions or Azure Functions have dashboards and Web APIs that expose information about the execution of functions.
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Comparison of FaaS Cloud Platforms [PDF]
, 2019 Üha enam arendatakse tarkvara pilves ning viimastel aastatel on tekkinud uus võimalus hostida pilves tervete rakenduste asemel ainult funktsioone. Selliseid lahendusi kutsutakse FaaS (Functions-as-a-Service) platvormideks ning käesolev töö annab ülevaate
Kodar, Mark-Eerik
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Characterization of containers in emerging applications: Microservices, FAAS and GPUS [PDF]
, 2018 Containers have enabled new computing paradigms such as Functions-as-a- Service in data centers today. Containers are inherently more lightweight than virtual machines.
Darbaz, Haldun Umur
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Function composition in function-as-a-service platforms
, 2023 Serverless computing is a paradigm that allows developers to focus on writing code without the need to manage the underlying infrastructure. Code is executed on-demand, automatically scaled, and billed during its execution time. Function-as-a-Service and cloud function composition, also known as cloud workflows, are among the most popular serverless ...
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source