Results 161 to 170 of about 5,311,244 (314)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Some Properties of Certain Analytic and Univalent Functions
, 2015 [[abstract]]In [2], Frasin and Jahangiri introduced the class B(μ, ) of analytic and univalent functions to give some properties for this class.
B. A. Frasin
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Motivic coaction on generalized hypergeometric functions
This thesis deals with the motivic coaction and single-valued map for hypergeometric functions. It is known that hypergeometric functions have series expansions whose coefficients can be expressed in terms of multiple zeta values and multiple ...
Kamlesh, Deepak
core +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Inclusion Criteria for Subclasses of Functions and Gronwall’s Inequality
, 2016 [[abstract]]A normalized analytic function f is shown to be univalent in the open unit disk D if its second coefficient is sufficiently small and relates to its Schwarzian derivative through a certain inequality. New criteria for analytic functions to be
A. Swaminathan +3 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Approach regions for the square root of the Poisson kernel and weak L^p boundary functions
, 1999 Let P 0 f(z) = P (z; fi)f(e ) dfi for f 2 L (T), where P (z; fi) is the Poisson kernel in the unit disc. In this paper we consider the convergence properties of the normalised operator P 0 f=P 0 1. We give a complete characterisation of the
Matematiskt Centrum +2 more
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source