Results 61 to 70 of about 5,311,244 (314)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

On Symmetric Functions and Symmetric Functions of Symmetric Functions

open access: yesThe Annals of Mathematical Statistics, 1931
The study of symmetric functions is quite an old one. From the time of Girard (1629) even up to the present day this sub. ject has occupied the attention of many eminent mathematicians. The theory of the roots of algebraic equations in one or more variables has furnished the chief incentive for the development of the theory of symmetric functions ...
openaire   +2 more sources

Non-continuous set-valued functions [PDF]

open access: yes, 1973
In [1] the concept of continuous set-valued functions is defined and developed. Somewhat continuous functions are defined in [2]. The purpose of this thesis is to extend the concept of somewhat continuity to set-valued functions and prove or disprove the
Fife, Earl Dennett   +1 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Luteolin Alleviates the TNF-α-Induced Inflammatory Response of Human Microvascular Endothelial Cells via the Akt/MAPK/NF-κB Pathway

open access: yesMediators of Inflammation
Endothelial dysfunction and pathological alterations are pivotal in the pathogenesis of cardiovascular disease. To date, effective interventions for these endothelial changes are lacking.
Qing-Yu Lu   +5 more
doaj   +1 more source

The summatory function of the Möbius function in function fields [PDF]

open access: yesActa Arithmetica, 2017
We study the growth rate of the summatory function of the Möbius function in the context of an algebraic curve over a finite field. Our work shows a strong resemblance to its number field counterpart, which was proved by Ng in 2004. We find an expression for a bound of the summatory function, which becomes sharp when the zeta zeros of the curve satisfy
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase

open access: yesNature Communications, 2019
RAD51 assembly on single-stranded DNAs is an important step in the homology-dependent repair of DNA damage. Here authors reveal a role for the human RAD51 paralogue, SWSAP1, as a regulator of RAD51 assembly, by antagonizing RAD51 remodeller, FIGNL1 AAA + 
Kenichiro Matsuzaki   +3 more
doaj   +1 more source

Busemann Functions and Barrier Functions [PDF]

open access: yesActa Applicandae Mathematicae, 2017
We show that Busemann functions on a smooth, non-compact, complete, boundaryless, connected Riemannian manifold are viscosity solutions with respect to the Hamilton-Jacobi equation determined by the Riemannian metric and consequently they are locally semi-concave with linear modulus.
Cui, Xiaojun, Cheng, Jian
openaire   +2 more sources

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