Results 121 to 130 of about 6,194,107 (299)
PharmaceuticalsErythroleukemia is a rare form of acute myeloid leukemia (AML). Its molecular pathogenesis remains vague, and this disease has no specific therapeutic treatments.
Jue Yang +8 more
doaj +1 more source
Additive Functionals and Excessive Functions
The Annals of Mathematical Statistics, 1965 During the past five or six years there has been much work done on the problem of representing excessive functions as the potentials of additive functionals. This is a natural generalization to Markov processes of the classical theorem of Riesz dealing with the representation of non-negative superharmonic functions as the potentials of measures.
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
On the semicontinuity of functionals on function spaces
Proceedings of the American Mathematical SocietyResults on the upper and lower semicontinuity of functionals defined on spaces of convex and more general functions are established. In particular, the following result is obtained. Let $ϕ(v; \cdot)$ be the density of the absolutely continuous part of a Radon measure $Φ(v; \cdot)$ associated to a function $v\colon X\rightarrow \mathbb{R}$ defined on ...
Baêta, Fernanda M., Ludwig, Monika
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
MoleculesAlthough the long-term survival rate for leukemia has made significant progress over the years with the development of chemotherapeutics, patients still suffer from relapse, leading to an unsatisfactory outcome.
Chaoyan Wang +12 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Natural Products and BioprospectingA chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb., has yielded eleven bohemamine dimers (1–11).
Dong-Yang Wang +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Flexible patient-specific instruments for maxillary repositioning during Le Fort I osteotomy
Advances in Oral and Maxillofacial Surgery, 2022 Taishi Ohtani +4 more
doaj +1 more source