Results 101 to 110 of about 6,194,107 (299)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity

open access: yesBMC Cancer, 2019
Background MAPK/ERK kinases transmit signals from many growth factors/kinase receptors during normal cell growth/differentiation, and their dysregulation is a hallmark of diverse types of cancers.
Ning Wang   +11 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Symmetric Functions, Noncommutative Symmetric Functions And Quasisymmetric Functions II

open access: yesActa Applicandae Mathematicae, 2003
This is part two of this survey; to appear in Acta. Appl. Math. The first part appeared in Acta Appl. Math 75 (2003), 55-93 and is also 'arXived'.
openaire   +8 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Postoperative nasal airway resistance is correlated with changes in anterior nasal cavity volume following posterior and superior movement caused by Le Fort I osteotomy

open access: yesAdvances in Oral and Maxillofacial Surgery
Purpose: This study aimed to analyse the relationship between changes in the anterior nasal cavity volume and nasal airway resistance following posterosuperior movement of the maxilla. Materials and methods: We studied 16 patients (13 female, 3 male) who
Jing Yuan   +5 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Function beyond function? Reflections on the functionality of the autonomous

open access: yesDe Musica Disserenda, 2006
Of all the arts, music has always seemed to be the most autonomous, free from the bonds and limits of representation. Hence its functionality within this very autonomy or non-functionality: its link with the sacred, elevation over the economics of survival, its ritual value.
openaire   +2 more sources

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