Results 171 to 180 of about 6,178,348 (299)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Lipschitz functions of continuous functions [PDF]
Pacific Journal of Mathematics, 1953 Marx, Imanuel, Piranian, George
openaire +3 more sources
Subclasses of Analytic Functions Defined by Carlson - Shaffer Linear Operator
, 2015 [[abstract]]We introduce the subclass LT (a, c; , ) of analytic functions with negative coefficients defined by the linear operator L(a, c)f(z) which introduced and studied by Carlson and Shaffer [4].
B. A. Frasin
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Penalized Likelihood-Based Estimation of Stratified Semiparametric Cox Models Under Partly Interval Censoring. [PDF]
Biom JMa J, Webb A, Manuguerra M, Hudson HM.
europepmc +1 more source
Inclusion Criteria for Subclasses of Functions and Gronwall’s Inequality
, 2016 [[abstract]]A normalized analytic function f is shown to be univalent in the open unit disk D if its second coefficient is sufficiently small and relates to its Schwarzian derivative through a certain inequality. New criteria for analytic functions to be
A. Swaminathan +3 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Understanding Patient Navigation Functions: A Qualitative Exploration of Navigators' Perspectives in Alberta, Canada. [PDF]
Health Serv InsightsBerzins S +3 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source