Results 91 to 100 of about 6,413,720 (299)
AbstractThis report describes the first scientific meeting of the British Society for Proteome Research (BSPR), which was organised jointly with the European Bioinformatics Institute (EBI) and held in July 2004. The focus of the conference was functional proteomics with an emphasis on possible clinical application. The main subjects described here are:
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Design and Synthesis of Flavonoidal Ethers and Their Anti-Cancer Activity In Vitro
Flavonoids are well-characterized polyphenolic compounds with pharmacological and therapeutic activities. However, most flavonoids have not been developed into clinical drugs, due to poor bioavailability.
Lu Jin +7 more
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ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
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Background Diabetic cardiomyopathy (DCM) is a cardiovascular complication, with cardiomyocyte senescence being a key pathological process. Cyclovirobuxine D (CVB-D), the active compound in Buxus sinica (Rehd. et Wils.) var. parvifolia M. Cheng. CVB-D has
Jiang-fei An +13 more
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ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
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ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
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Functionals on continuous functions [PDF]
Baxter, J. R., Chacon, R. V.
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Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity
Background MAPK/ERK kinases transmit signals from many growth factors/kinase receptors during normal cell growth/differentiation, and their dysregulation is a hallmark of diverse types of cancers.
Ning Wang +11 more
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ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth +5 more
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Synthesis of Flavone Derivatives via N-Amination and Evaluation of Their Anticancer Activities
Seventeen new flavone derivatives substituted at the 4′-OH position were designed, synthesized and evaluated for their anticancer and antibacterial activities.
Ni Zhang +7 more
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