Results 101 to 110 of about 3,409,433 (269)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A New Indole Derivative, LWX-473, Overcomes Glucocorticoid Resistance in Jurkat Cells by Activating Mediators of Apoptosis

Frontiers in Bioscience-Landmark
Background: Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL). However, the development of GC resistance limits their prolonged use.
Jingrui Song, Kun Yang, Babu Gajendran, Krishnapriya M. Varier, Wenxue Li, Qin Liu, Qing Rao, Yubing Hang, Xiangchun Shen, Sheng Liu, Lei Huang, Mei Xu, Yanmei Li   +12 more
doaj   +1 more source

Spatial Function-on-Function Regression

Journal of Agricultural, Biological and Environmental Statistics
43 pages, 6 figures, 3 ...
Ufuk Beyaztas, Han Lin Shang, Gizel Bakicierler Sezer, Abhijit Mandal, Roger S. Zoh, Carmen D. Tekwe   +5 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A Carbon 21 Steroidal Glycoside with Pregnane Skeleton from Cynanchum atratum Bunge Promotes Megakaryocytic and Erythroid Differentiation in Erythroleukemia HEL Cells through Regulating Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway

Pharmaceuticals
Erythroleukemia is a rare form of acute myeloid leukemia (AML). Its molecular pathogenesis remains vague, and this disease has no specific therapeutic treatments.
Jue Yang, Chaolan Pan, Yang Pan, Anlin Hu, Peng Zhao, Meijun Chen, Hui Song, Yanmei Li, Xiaojiang Hao   +8 more
doaj   +1 more source

Additive Functionals and Excessive Functions

The Annals of Mathematical Statistics, 1965
During the past five or six years there has been much work done on the problem of representing excessive functions as the potentials of additive functionals. This is a natural generalization to Markov processes of the classical theorem of Riesz dealing with the representation of non-negative superharmonic functions as the potentials of measures.
openaire   +3 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

On the semicontinuity of functionals on function spaces

Proceedings of the American Mathematical Society
Results on the upper and lower semicontinuity of functionals defined on spaces of convex and more general functions are established. In particular, the following result is obtained. Let $ϕ(v; \cdot)$ be the density of the absolutely continuous part of a Radon measure $Φ(v; \cdot)$ associated to a function $v\colon X\rightarrow \mathbb{R}$ defined on ...
Baêta, Fernanda M., Ludwig, Monika
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Dibohemamines I–O from Streptomyces sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Houttuynia cordata Thunb.

Natural Products and Bioprospecting
A chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb., has yielded eleven bohemamine dimers (1–11).
Dong-Yang Wang, Ming-Xing Li, Yan-Chao Xu, Peng Fu, Wei-Ming Zhu, Li-Ping Wang   +5 more
doaj   +1 more source