Results 31 to 40 of about 3,378,229 (268)

Two New 4-Hydroxy-2-pyridone Alkaloids with Antimicrobial and Cytotoxic Activities from Arthrinium sp. GZWMJZ-606 Endophytic with Houttuynia cordata Thunb

Molecules, 2023
Two new 4-hydroxy-2-pyridone alkaloids furanpydone A and B (1 and 2), along with two known compounds N-hydroxyapiosporamide (3) and apiosporamide (4) were isolated from the endophytic fungus Arthrinium sp.
Ying Yin, Dongyang Wang, Dan Wu, Wenwen He, Mingxing Zuo, Weiming Zhu, Yanchao Xu, Liping Wang   +7 more
doaj   +1 more source

The Background of a Patient Undergoing Long-Term Periodontal Disease Maintenance Using Step for Coding and Theorization: A Case Report

Case Reports in Dentistry
Periodontal maintenance is crucial for long-term periodontal stability, but some patients do not undertake maintenance following their initial treatment.
Kosuke Muraoka, Masaki Morishita, Taiji Nakamura, Keisuke Nakashima, Shuji Awano   +4 more
doaj   +1 more source

Regioselective alkali metal reduction of dibenzocyclooctadiene lignan derivatives, demethoxylation followed by dehalogenation

Chemistry Central Journal, 2017
The regioselective demethoxylation and dehalogenation of dihalogenated dibenzocyclooctadiene lignans derivatives were realized in a one-step reaction with excellent yields in the sodium and t-butanol reaction system.
Qing-yao Wang, Jia-qi Fang, Lu-lu Deng, Xiao-jiang Hao, Shu-zhen Mu   +4 more
doaj   +1 more source

Determination of a Wave Function Functional [PDF]

Physical Review Letters, 2004
In this paper we propose the idea of expanding the space of variations in standard variational calculations for the energy by considering the wave function $ψ$ to be a functional of a set of functions $χ: ψ= ψ[χ]$, rather than a function. In this manner a greater flexibility to the structure of the wave function is achieved.
Pan, Xiao-Yin, Sahni, Viraht, Massa, Lou
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

UM171 cooperates with PIM1 inhibitors to restrict HSC expansion markers and suppress leukemia progression

Cell Death Discovery, 2022
The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells Expansion (HSCE), but its impact on leukemia is not known. Herein, we show in a mouse model of erythroleukemia that UM171 strongly suppresses leukemia progression.
Anling Hu, Jian Gao, Krishnapriya M. Varier, Babu Gajendran, Fei Jiang, Wuling Liu, Chunlin Wang, Xiao Xiao, Yanmei Li, Eldad Zacksenhaus, Sajjad Ali, Yaacov Ben-David   +11 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Demographic and environmental factors associated with disability in India, Laos, and Tajikistan: a population-based cross-sectional study

BMC Public Health, 2022
Background The number of people experiencing functional limitations due to health conditions (capacity) is expected to increase in low and middle-income countries as populations age and rates of non-communicable disease rise.
Michael Zhu Chen, Lindsay Lee, Carolina Fellinghauer, Alarcos Cieza, Somnath Chatterji   +4 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

BMC Cancer, 2021
Background Cholesterol plays vital roles in human physiology; abnormal levels have deleterious pathological consequences. In cancer, elevated or reduced expression of cholesterol biosynthesis is associated with good or poor prognosis, but the underlying ...
Fang Yu, Babu Gajendran, Ning Wang, Klarke M. Sample, Wuling Liu, Chunlin Wang, Anling Hu, Eldad Zacksenhaus, Xiaojiang Hao, Yaacov Ben-David   +9 more
doaj   +1 more source