Results 91 to 100 of about 895 (256)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Some generalizations of Opial's inequality, Hermite-Hadamard's inequality and applications

open access: yes, 2013
博士本篇論文共分為四章。第一章中,我們探討Opial所提出的不等式。因為Opial不等式有連續型跟離散型的情形,所以我們希望透過時間尺度(time scales)的觀念將二者結合。 第二章中我們提出了一些Opial不等式在時間尺度上的一些推廣。 第三章中,我們探討赫米提-阿達瑪(Hermite-Hadamard)與費伊爾(Fejer)所提出的不等式。之後並談論一些有關阿達瑪與費伊爾不等式的改善。 最後在第四章中,我們將談論在第三章結果的應用,分別為特殊平均數、隨機變數與加權梯形公式。In this ...
羅仁傑; Lo, Jen-Chieh
core  

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

Sequential Nonparametric Detection of High-Dimensional Signals under Dependent Noise

open access: yes, 2015
This thesis deals with sequential nonparametric detection schemes for high-dimensionalsignals, i.e. with the identification of a change-point in a given data set of a discretelysampled signal, where we allow for dependent noise as error terms.
Prause, Annabel
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

About the general chain rule for functions of bounded variation

open access: yesNonlinear Analysis
We give an alternative proof of the general chain rule for functions of bounded variation ([ADM90]), which allows to compute the distributional differential of $φ\circ F$, where $φ\in \mathrm{LIP}(\mathbb{R}^m)$ and $F\in\mathrm{BV}(\mathbb{R}^n,\mathbb{R}^m)$.
Brena C., Gigli N.
openaire   +4 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

$BV$ spaces and rectifiability for Carnot-Carathéodory metrics: an introduction [PDF]

open access: yes, 2002
summary:This paper is meant as a (short and partial) introduction to the study of the geometry of Carnot groups and, more generally, of Carnot-Carathéodory spaces associated with a family of Lipschitz continuous vector fields.
Franchi, Bruno, Bruno Franchi
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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