Results 111 to 120 of about 44,268 (306)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Polish Proper Names in Literary Translation – Difficulties and Challenges (Based on Zygmunt Miłoszewski’s Crime Trilogy and its French Translation)

Studies in Logic, Grammar and Rhetoric
In a literary translation, nomina propria not only indicate a given object, but also perform other functions, evoking many associations. As linguistic carriers of national culture, on the one hand, they introduce the element of foreignness to a ...
Kochanowska Urszula
doaj   +1 more source

Proper Names as Structures of Affinity and Recognition: A Cognitive Study (on the Basis of Three Languages: French, Polish, Ukrainian

, 2020
In the article we outline some characteristics of proper names as a linguistic phenomenon, their communicative and compositional features, stylistic functions and interpretive-perceptual models.
Piskozoub, Zoriana, Kost, Hanna
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Proper names in English Noun-Name constructs

, 2019
Working on the assumption that proper names and appellative nouns form prototypical categories with fuzzy boundaries (Van Langendonck 2007; Van Langendonck and Van De Velde 2016), this paper addresses the question how proper names, which identify ...
Cacchiani
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Linguosemiotics of Proper Names in Novel ‘Night Watch’ by S. Lukyanenko

Научный диалог
This article addresses the issue of linguosemiotic interpretation of proper names functioning in a literary text. The research aims to identify the linguosemiotic specificity of onyms through which the fantastic world of the work in the urban fantasy ...
N. V. Labunets, D. E. Ertner, E. N. Ertner   +2 more
doaj   +1 more source

A comparative analysis of functions served by characters’ proper names in Terry Pratchett’s “The Fifth Elephant” and its Polish translation

This study is devoted to the issue of the functions served by characters’ proper names in novels and their translations. The works of art chosen for analysis are Terry Pratchett’s “The Fifth Elephant” and the Polish translation of this book entitled ...
Gibka, Martyna Katarzyna
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source