Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
On the Origin of Some Theonyms of the Shaman Pantheon of the Altaians [PDF]
The paper gives a first look on theonyms, or proper names of deities, representing the shaman pantheon of the Altaians, figuratively called the “iron-head black guys”: Temir-kaan, Kömurkaan, Köö-kaan, Kerey-khaan, Padysh-Kerey, Piy Maatyr (Bai Maatyr ...
Nadezhda R. Oinotkinova
doaj +1 more source
The article deals with the analysis of the structure and functioning of the proper names of Arab educational migrants. The authors have identified and described the general features of the construction of Arab anthroponyms and the problems of intercultural communication.
L. Kuplevatska, Т. Manivska
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
PROPER NAMES OF THE SEAS: STRUCTURE, ORIGIN, FUNCTIONING IN UKRAINIAN LANGUAGE
The main goal of our research is to collect, systematize and analyze the proper names of all seas that are in the Ukrainian language. The purpose of the research involves solving the following tasks: 1) to draw up a register of pelagonyms; 2) determine their denotative and characteristic features; 3) find out etymological and word-forming features; 4 ...
M. M. Torchynskyi, N. M. Torchynska
openaire +3 more sources
O Evangelho Segundo Jesus Cristo, by Saramago: an anthroponomical reading
The subject of this paper is a symbolic and etymological analysis of the characters’ names from O Evangelho Segundo Jesus Cristo by José Saramago. This study aims to verify how the names are related to their functions in the literary work and to their ...
Kleber Eckert, Maiquel Röhrig
doaj +1 more source
Функции поэтонимов и способы их введения в контекст «Русских народных сказок» А. Н. Афанасьева [PDF]
. The article deals with the functions of proper names and ways of introduction characters’ names into the context of “Russian folk tales” by A. N. Afanasyev. Proper nouns not only identify the character but make the stress upon his peculiarities which
Апоненко, И.Н.
core
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Функціїї текстотворення політичних та військових онімів у мемуарах Вінстона Черчилля «my early life» (The text creation functions of separate groups of proper names in the Winston Churchill’s memoirs «My Early Life») [PDF]
У статті показані основні текстотвірні функції окремих груп власних назв в мемуарах Вінстона Черчилля «My Early Life». В центрі уваги автора знаходяться групи політичних та військових онімів, що складають значну частину внутрішнього текстового ...
Колосова, Г. (H. Kolosova)
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

