Results 71 to 80 of about 44,268 (306)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Studies on the Usage of Proper Names in Poems

open access: yes, 2005
Die Arbeit beginnt mit einer umfassenden sprachphilosophischen Analyse der Zeichenkategorie "Eigenname" und der Referenz literarischer Texte.
Gottschalk, Jürn
core   +1 more source

A Search for Origins : Proper Names in The Story of Kullervo [PDF]

open access: yes, 2020
In this thesis, I examine the proper names found in J.R.R. Tolkien’s adaptation The Story of Kullervo and their relation to the source text, the Kullervo cycle found in the Finnish epic Kalevala.
Sarre, Silvia
core  

"There are not enough mouths to utter all your fleeting names, o water" — proper names in Wisława Szymborska's works

open access: yes, 2021
Utwory Wisławy Szymborskiej doczekały się wielu opracowań, zwłaszcza literaturoznawczych. Badacze (np. S. Balbus, E. Balcerzan, A. Legeżyńska) szczegółowo omówili najważniejsze tematy tej poezji oraz cechy jej poetyki.
Graf, Magdalena
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Die Verarbeitung von Eigennamen im Mandarin-Chinesischen : eine Verhaltens- und Neuroimaging-Studie

open access: yes, 2006
Yen H-L. Processing of proper names in Mandarin Chinese : a behavioral and neuroimaging study. Bielefeld (Germany): Bielefeld University; 2006.Proper names have been considered as a universal language class (Bright, 2003; Müller 2004).
Yen, Huei-Ling
core  

Acquisition of Czech Language and Sphere of Proper Names of Language

open access: yes, 2014
The author analyzes two textbooks prepared for teaching Czech as a foreign language (A1 level) for the use of proper names for glottodidactic purposes.
Balowski, Mieczysław
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

PROPER NAMES OF THE SEAS: STRUCTURE, ORIGIN, FUNCTIONING IN UKRAINIAN LANGUAGE

open access: yesOpera in Linguistica Ukrainiana
The main goal of our research is to collect, systematize and analyze the proper names of all seas that are in the Ukrainian language. The purpose of the research involves solving the following tasks: 1) to draw up a register of pelagonyms; 2) determine their denotative and characteristic features; 3) find out etymological and word-forming features; 4 ...
M. M. Torchynskyi, N. M. Torchynska
openaire   +3 more sources

The numerical code in political media discourse (exemplified by proper names) [PDF]

open access: yesАктуальные проблемы филологии и педагогической лингвистики
The article deals with the role of the numerical code in modern political media discourse. The research aims to identify and analyze the peculiarities of contextual and discursive use of numerals in the structure of proper names used in political ...
Elena V. Dziuba
doaj   +1 more source

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