Results 111 to 120 of about 3,479,269 (175)

In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Conventional clinical trials remain the benchmark for evaluating therapeutic safety and efficacy, yet they are constrained by escalating costs, withdrawal over the extended follow‐up periods, recruitment difficulties, ethical limits, and a restricted ability to characterize heterogeneous populations.
Maximilian Balmus   +7 more
wiley   +1 more source

Considerations for the Integration of Clinical Trials and Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
As clinical decision‐making increasingly moves toward individualized and context‐specific treatment recommendations, reliance on any single evidence source, randomized or observational, may be insufficient. Principled integration of randomized controlled trials and real‐world data, grounded in explicit causal frameworks, offers a path toward evidence ...
Sky Qiu   +19 more
wiley   +1 more source

Genes Affecting Cotton Fiber Length: A Systematic Review and Meta-Analysis. [PDF]

open access: yesPlants (Basel)
Jiao J   +7 more
europepmc   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

open access: yesClinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila   +5 more
wiley   +1 more source

The Price of Circularity: Exploring the Determinants of Consumer Willingness to Pay

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The transition towards a circular economy (CE) requires not only technological and organisational innovation but also consumer engagement in adopting circular products. A key driver of this process is consumers' stated willingness to pay (WTP) a premium, which remains constrained by psychological, perceptual and contextual barriers.
Valerio Muto   +3 more
wiley   +1 more source

Readiness and Maturity for a Smart Circular Economy to Enhance Sustainability Performance: A Multidimensional Framework for the Hospitality Sector

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Research on readiness and maturity for the smart circular economy (SCE) remains fragmented, especially in the hospitality sector. This study develops a multidimensional framework that integrates the principles of the circular economy, Industry 4.0, and sustainability performance in the context of tourist accommodations.
Rafael Mora‐Contreras   +5 more
wiley   +1 more source

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