Results 211 to 220 of about 4,360,675 (386)

Administrative Protection of Public Funds

الرافدین للحقوق
Safar Spendari, Hassan Albannan
openaire   +2 more sources

Social Equity in Public Administration: The Work of the Federation of Southern Cooperatives/Land Assistance Fund

, 2013
Ramatoulaye Siby
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

ZOVER 2.0: a virome-based platform for zoonotic and vector-borne viruses. [PDF]

Nucleic Acids Res
Liu B, Zhu L, Zhou S, Li A, Xu P, Han Y, Shu Y, Chen L, Yang J, Wu Z.   +9 more
europepmc   +1 more source

Type I and type II corticosteroid receptor gene expression in the rat: effect of adrenalectomy and dexamethasone administration.

Molecular Endocrinology, 1989
J. M. Reul, P. Pearce, J. Funder, Z. Krozowski   +3 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Optimization Strategies for Scientific Research Fund Management in Provincial Local Universities under the Background of the "Streamlining Administration, Delegating Powers, and Improving Services" Reform [PDF]

Xiufen Bao

openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A novel, standardised approach to balancing effectiveness, efficiency and utility of surveillance AI prediction models for hospitalised patients using sepsis prediction as an exemplar. [PDF]

J Am Med Inform Assoc
van der Vegt AH, Campbell VK, Webb R, Venkatesh B, Lane PJ, Wilks K, McPhail S, Rice M, Isaacs T, Abdel-Hafez A, Whebell S, Irwin A, Schnetler RJ, Shetty A, Scott IA.   +14 more
europepmc   +1 more source

Local Administration Funding and Regional Disparities in Italy Before WW1

, 2011
Patrizia Battilani
openalex   +1 more source