Results 141 to 150 of about 6,173,924 (311)

Annual report of the Client Security Fund Committee. 2007.

open access: yes, 2008
Annual; Began in 2006?; "Pursuant to Practice Book [section] 2-72(e), the following is a report of claims filed with the Client Security Fund Committee during calendar year ..., and on the Committee's activities during ... in connection with claims filed
Connecticut. Client Security Fund Committee.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Historical pension funds performance and application of a selection criteria based on the probability of loss

open access: yesContabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas, 2014
This paper proposes a new methodology for selecting a pension fund base on the probability of loss for its customers. The methodology includes the historical performance of the portfolio between, March 2006 and May 2013, and projects its profitability ...
Juan Carlos Ames Santillán
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hedge Fund Replication ?Revised in November 2008, forthcoming in The Recent Trend of Hedge Fund Strategies) [PDF]

open access: yes
This chapter provides a comprehensive explanation of hedge fund replication. This chapter first reviews the characteristics of hedge fund returns. Then, the emergence of hedge fund replication products is discussed.
Kyo Yamamoto, Akihiko Takahashi
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Annual report; Annual report, Client's Security Fund of Ohio; Supreme Court of Ohio : ... annual report, Client's Security Fund of Ohio; Annual report of the Supreme Court of Ohio Clients' Security Fund

open access: yes, 2004
Electronic coverage as of Oct. 29, 2007: 17th (2002)-; At head of cover title: Supreme Court of Ohio.; Covers the fiscal year: July 1-June 30.; Harvested from the web on 7/6/10The Client's Security Fund provides assistance to clients who have been ...
Clients' Security Fund of Ohio.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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