Results 151 to 160 of about 30,704 (318)

Incentive Contracts and Hedge Fund Management

We investigate incentive effects of a typical hedge-fund contract for a manager with power utility. With a one-year horizon, she displays risk-taking that varies dramatically with fund value.
Hodder, James E., Jackwerth, Jens Carsten   +1 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Health of Nations Fund: Financing global drug development. [PDF]

PLOS Glob Public Health
Cho J, Singh M, Zhao C, Chaudhuri SE, Lo AW.   +4 more
europepmc   +1 more source

International Mutual Fund Flows

, 2005
The last few decades has witnessed a dramatic growth of U.S. based mutual funds that invest in non-U.S. stock markets. Yet we know little about what drives U.S. households to invest in these funds.
Patro, Dilip K.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A whole rock geochemical dataset for magmatic rocks drilled on the mid-Norwegian margin. [PDF]

Sci Data
Tegner C, Guo P, Chatterjee S, Lambart S, Jones MT, Planke S, Svensen HH, Neumann ER, Lesher CE, Cashman K, Takahashi T, Cunningham EH, Morris AM, Stokke EW, Millett JM, Mohn GTF, Longman J, Berndt C, Alvarez Zarikian CA, Betlem P, Ferré EC, Filina IY, Frieling J, Harper DT, Scherer RP, Varela N, Xu W.   +26 more
europepmc   +1 more source

Is Ethical Money Financially Smart?

Little is known about how investors select socially responsible investment (SRI) funds.Investors in SRI funds may care more about social or ethical issues in their investment decisions than about fund performance.This paper studies the money-flows into ...
Horst, J.R. ter, Zhang, C., Renneboog, L.D.R.   +2 more
core  

Determinants of Corporate Bond Mutual Fund Flows

This paper examines the determinants of investor flows into U.S. corporate bond mutual funds, with a focus on monetary policy and fund-specific characteristics during the COVID-19 crisis.
Jeske, Vanessa
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Compulsory health insurance in the Central and Eastern European countries: the similarity and the difference with Social Health Insurance. [PDF]

Front Public Health
Shishkin S.
europepmc   +1 more source