Results 181 to 190 of about 30,704 (318)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Turbulent dynamo in the terrestrial magnetosheath. [PDF]

Nat Commun
Vörös Z, Roberts OW, Narita Y, Yordanova E, Nakamura R, Settino A, Schmid D, Volwerk M, Simon Wedlund CL, Varsani A, Sorriso-Valvo L, Bourdin PA, Kis Á.   +12 more
europepmc   +1 more source

Do Sophisticated Investors Believe in the Law of Small Numbers?

Believers in the law of small numbers tend to overinfer the outcome of a random process after a small series of observations. They believe that small samples replicate the probability distribution properties of the population.
Baquero, G., Verbeek, M.J.C.M.
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Second-order asymptotics of fractional Gagliardo seminorms as s → 1 - and convergence of the associated gradient flows. [PDF]

Fract Calc Appl Anal
Kubin A, Pagliari V, Tribuzio A.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Management discussion of laws and regulations on human genetic resources in China: a scoping review. [PDF]

BMC Med Ethics
Sun Q, Liu Y, Huang J, Zhang Y, Wang K.
europepmc   +1 more source

On the Behavior of Mutual Fund Investors and Managers.

: This thesis investigates empirically and theoretically the behavior of mutual fund investors and managers. These two aspects are closely related to each other.
Goriaev, A.P.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Promoting sustainable development worldwide in the metacoupled anthropocene. [PDF]

Nat Commun
Jiang Q, Xu Z, Bhattarai N, Lin Y, Xiao H, Ren J, Pahlow M, Jiang Z, Liu Y, Wu X, Ye G, Zhang H, Li J, Zhu P, Liang S, Cui Y, Liao C, Dong L, Liu J.   +18 more
europepmc   +1 more source