Results 251 to 260 of about 9,261,605 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ViralQC: a tool for assessing completeness and contamination of predicted viral contigs. [PDF]

Bioinformatics
Peng C, Shang J, Guan J, Sun Y.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Effects of Repeated Partial Daily Social Isolation and Treadmill Exercise on Spatial Memory and Hippocampal Long-Term Potentiation in Male Rats. [PDF]

Int J Dev Neurosci
Ezgin N, Yousef M, Cevik ÖS, Suer C, Sahin L.   +4 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Donor Right Ventricular Oversizing Is Independently Associated With Severe Primary Graft Dysfunction After Heart Transplantation: A Multicenter Retrospective Analysis. [PDF]

Clin Transplant
Ahmad A, Wang CC, Petrovic M, Williams AM, Trahanas J, Bommareddi S, Absi T, Quintana E, McGann K, Thaivalappil A, Eidson C, Navid W, Siddiqi H, Brinkley M, Tsai S, Rali AS, Menachem JN, Pedrotty D, Sacks S, Zalawadiya S, Bacchetta M, Lindenfeld J, Schlendorf K, Shah AS, Lima B.   +24 more
europepmc   +1 more source

Spectral-Kinetic Synergy in Au-Network Engineered FeTiO₃: A Multi-Field Coupling Strategy for Lunar In Situ Resource Utilization. [PDF]

Adv Sci (Weinh)
Wang Y, Wang Q, Leong P, Feng S, Wang M, Mo R, Shi X, Li X, Zhu G, Tang C.   +9 more
europepmc   +1 more source

Development and interpretability of a machine learning model for postoperative hypothermia prediction in placenta previa Cesarean section: A retrospective cohort study. [PDF]

J Int Med Res
Zhu Y, Xie D, Liang R, Zhou CM.
europepmc   +1 more source

Risk-taking responses to crash experience: Evidence from China. [PDF]

PLoS One
Fang Z, Xu H, Mu Y.
europepmc   +1 more source

Plasma neurofilament light for early differentiation of multiple system atrophy from Parkinson disease. [PDF]

EBioMedicine
Yu Z, Zheng Y, Kou W, Cai H, Li S, Wu J, Yang C, Zhu B, Liu G, Wang Y, Tian H, Zhang X, Zhou Y, Liu X, Chang Y, Chen Z, Mao W, Feng T.   +17 more
europepmc   +1 more source