Results 91 to 100 of about 25,337,233 (257)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Modelling and Predicting the Stock Price of the Pharmaceutical and Chemical Companies Listed on the Stock Exchange via New Methods and Models [PDF]

open access: yesحسابداری سلامت, 2015
Introduction: In this research, econometrics and Radial Base Function neural networks have been used to increase the effectiveness, decrease time and costs for predicting the stock price of the material industries and pharmaceutical products, and the ...
O. Aman Dad, M. Salehi, M. Fallahi
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On the Brauer-Manin obstruction for degree-four del Pezzo surfaces [PDF]

open access: yes, 2016
We show that for every integer 1≤d≤4 and every finite set S of places, there exists a degree-d del Pezzo surface X over Q such that Br(X)/Br(Q)≅Z/2Z and the nontrivial Brauer class has a nonconstant local evaluation exactly at the places in S.
Fundamental mathematics   +3 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ASSESSMENT OF EFFICIENCY OF PIOTROSKI F-SCORE STRATEGY IN THE WARSAW STOCK EXCHANGE

open access: yesResearch on Enterprise in Modern Economy Theory and Practice, 2022
Magdalena Kusowska
doaj   +1 more source

Tools for fundamental analysis functions of TCR repertoires: a systematic comparison. [PDF]

open access: yesBrief Bioinform, 2020
Zhang Y   +12 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Fundamental Analysis of Shares of PT Indocement Tunggal Prakarsa Tbk. and PT Semen Indonesia (Persero) Tbk. (2019-2023)

open access: yesJurnal Iqtisad
It is important to note that stock investment instruments that offer substantial profits relative to other investment instruments inherently carry investment risks, which must be carefully considered by prospective investors.
Asiroch Yulia Agustina, Nurhadi Fadillah
doaj   +1 more source

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