Results 131 to 140 of about 138,321 (260)

Chern networks: reconciling fundamental physics and device engineering. [PDF]

Nat Commun
Gilbert MJ.
europepmc   +1 more source

Cosmology and Fundamental Physics with the Euclid Satellite. [PDF]

Living Rev Relativ, 2013
Amendola L, Appleby S, Bacon D, Baker T, Baldi M, Bartolo N, Blanchard A, Bonvin C, Borgani S, Branchini E, Burrage C, Camera S, Carbone C, Casarini L, Cropper M, de Rham C, Di Porto C, Ealet A, Ferreira PG, Finelli F, García-Bellido J, Giannantonio T, Guzzo L, Heavens A, Heisenberg L, Heymans C, Hoekstra H, Hollenstein L, Holmes R, Horst O, Jahnke K, Kitching TD, Koivisto T, Kunz M, La Vacca G, March M, Majerotto E, Markovic K, Marsh D, Marulli F, Massey R, Mellier Y, Mota DF, Nunes NJ, Percival W, Pettorino V, Porciani C, Quercellini C, Read J, Rinaldi M, Sapone D, Scaramella R, Skordis C, Simpson F, Taylor A, Thomas S, Trotta R, Verde L, Vernizzi F, Vollmer A, Wang Y, Weller J, Zlosnik T, Euclid Theory Working Group.   +63 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cosmology and fundamental physics with the ELT-ANDES spectrograph. [PDF]

Exp Astron (Dordr)
Martins CJAP, Cooke R, Liske J, Murphy MT, Noterdaeme P, Schmidt TM, Alcaniz JS, Alves CS, Balashev S, Cristiani S, Di Marcantonio P, Génova Santos R, Gonçalves RS, González Hernández JI, Maiolino R, Marconi A, Marques CMJ, Melo E Sousa MAF, Nunes NJ, Origlia L, Péroux C, Vinzl S, Zanutta A.   +22 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

In Our Mind's Eye: Thinkable and Unthinkable, and Classical and Quantum in Fundamental Physics, with Schrödinger's Cat Experiment. [PDF]

Entropy (Basel)
Plotnitsky A.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Achieving ultra-low and -uniform residual magnetic fields in a very large magnetically shielded room for fundamental physics experiments. [PDF]

Eur Phys J C Part Fields
Ayres NJ, Ban G, Bison G, Bodek K, Bondar V, Bouillaud T, Bowles D, Chanel E, Chen W, Chiu PJ, Crawford CB, Naviliat-Cuncic O, Doorenbos CB, Emmenegger S, Fertl M, Fratangelo A, Griffith WC, Grujic ZD, Harris PG, Kirch K, Kletzl V, Krempel J, Lauss B, Lefort T, Lejuez A, Li R, Mullan P, Pacura S, Pais D, Piegsa FM, Rienäcker I, Ries D, Pignol G, Rebreyend D, Roccia S, Rozpedzik D, Saenz-Arevalo W, Schmidt-Wellenburg P, Schnabel A, Segarra EP, Severijns N, Svirina K, Tavakoli Dinani R, Thorne J, Vankeirsbilck J, Voigt J, Yazdandoost N, Zejma J, Ziehl N, Zsigmond G, nEDM Collaboration At Psi T.   +50 more
europepmc   +1 more source