Results 71 to 80 of about 138,321 (260)

Superconducting Quantum Sensors for Fundamental Physics Searches

Physical Sciences Forum
Superconducting Transition Edge Sensors (TESs) are a promising technology for fundamental physics applications due to their low dark count rates, excellent energy resolution, and high detection efficiency.
Gulden Othman, Robert H. Hadfield, Katharina-Sophie Isleif, Friederike Januschek, Axel Lindner, Manuel Meyer, Dmitry Morozov, Devendra Kumar Namburi, Elmeri Rivasto, José Alejandro Rubiera Gimeno, Christina Schwemmbauer   +10 more
doaj   +1 more source

Jackiw-Teitelboim gravity and rotating black holes

Journal of High Energy Physics, 2019
We show that the free energy at low temperatures for near-extremal black holes is correctly obtained from the Jackiw-Teitelboim (JT) model of gravity. Our arguments apply to all black holes, including rotating ones, whose metric has a near-horizon AdS2 ...
Upamanyu Moitra, Sunil Kumar Sake, Sandip P. Trivedi, V. Vishal   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Possible Tests of Fundamental Physics with GINGER

Astronomy
The GINGER (gyroscopes in general relativity) project foresees the construction of an array of large frame ring laser gyroscopes, rigidly connected to the Earth.
Giuseppe Di Somma, Carlo Altucci, Francesco Bajardi, Andrea Basti, Nicolò Beverini, Salvatore Capozziello, Giorgio Carelli, Simone Castellano, Donatella Ciampini, Gaetano De Luca, Angela D. V. Di Virgilio, Francesco Fuso, Francesco Giovinetti, Enrico Maccioni, Paolo Marsili, Antonello Ortolan, Alberto Porzio, Matteo Luca Ruggiero, Raffaele Velotta   +18 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A way forward for fundamental physics in space. [PDF]

NPJ Microgravity, 2022
Bassi A, Cacciapuoti L, Capozziello S, Dell'Agnello S, Diamanti E, Giulini D, Iess L, Jetzer P, Joshi SK, Landragin A, Poncin-Lafitte CL, Rasel E, Roura A, Salomon C, Ulbricht H.   +14 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Detection of early-universe gravitational-wave signatures and fundamental physics. [PDF]

Gen Relativ Gravit, 2022
Caldwell R, Cui Y, Guo HK, Mandic V, Mariotti A, No JM, Ramsey-Musolf MJ, Sakellariadou M, Sinha K, Wang LT, White G, Zhao Y, An H, Bian L, Caprini C, Clesse S, Cline JM, Cusin G, Fornal B, Jinno R, Laurent B, Levi N, Lyu KF, Martinez M, Miller AL, Redigolo D, Scarlata C, Sevrin A, Haghi BSE, Shu J, Siemens X, Steer DA, Sundrum R, Tamarit C, Weir DJ, Xie KP, Yang FW, Zhou S.   +37 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source